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Epigenetic mechanisms mediate microbiome effects on immunity
In contrast to hepatocytes, where secretion is constant and poorly controlled, cholangiocyte secretion is broadly regulated.5, 6 Kupffer Cells Also known as Browicz-Kupffer cells or stellate macrophages , these cells represent 2% to 5% of the liver cell mass, and are specialized macrophages localized to the sinusoids as part of the mononuclear phagocyte system
Consequently, glycolysis remains their sole source of ATP

To develop anticancer therapeutics, the issue of poor bioavailability of phytocompounds needs to be addressed

Gastroenterology 144 , 903911.e3 (2013)
