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By using tetrahexyldecyl ascorbate as a lipid-soluble form of vitamin C, the serum sinks deep into the skin, protecting it against free radicals with no irritation

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Injections were performed into the DMH (bregma: 1.50 mm, midline: 0.35 mm, dorsal surface: 4.90 mm) and vlPOA (bregma: 0.10 mm, midline: 0.70 mm, dorsal surface: 5.60 mm) at a rate of 30 nL/min using a micromanipulator (Narishige, East Meadow, NY, USA), allowing 10 min for each injection