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While cobalt occurs naturally in the soil, it does not do so predictably

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Concurrent medications (metformin, PPIs, antibiotics) and underlying gastrointestinal conditions may cause diarrhoea coinciding with B12 supplementation

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Thiamine is not stored in the body, so daily intake is necessary

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For instance, EPO may promote angiogenesis and reduce apoptosis (1)

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Both cagrilintide (an amylin analogue) and GLP-1 agonists (semaglutide, tirzepatide) delay gastric emptying through overlapping mechanisms, and dosing them simultaneously compounds nausea risk

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