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Here we report adenine base editor (ABE) and cytosine base editor (CBE) screens to evaluate the WNT signaling phenotype of mutations introduced across endogenous gene loci encoding BDC components 17,18,19,20,21

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Therefore, further research is needed to fully understand and harness the potential of O-GlcNAcylation in the treatment of ischemic stroke

Musa et al

However, transfection efficiency and gene expression are limited compared to viral transduction systems