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Lysine Catabolism The major site of lysine catabolism in humans is the mitochondria in the liver

Since Complex I and III are often heralded as the chief sites of mitochondrial ROS production, other sites including 2-oxoglutarate dehydrogenase (Odh), branched chain amino acid dehydrogenase (Bckdh), pyruvate dehydrogenase (Pdh), Sdh, dihydroorotate dehydrogenase, FAD-linked glycerol-3-phosphate dehydrogenase, proline dehydrogenase, and electron transfer flavoprotein ubiquinone:oxidoreductase are often overlooked (Murphy, 2012a)

[DOI] [PubMed] [Google Scholar] 4.Doehner W., Frenneaux M., Anker S

Schmoll, D