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These findings are significant because it implies that hydrogen rich saline may be able to play a therapeutic role in insulin resistance and diabetes mellitus [31]

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Research indicates that most of the intravenously administered EXOs are quickly removed from circulation by the mononuclear phagocyte system in a matter of minutes, thus reducing their therapeutic range (Honda et al., 2025)

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doi: 10.3389/fcimb.2021.615959 33 ZhangHZengJLiJGongHChenMLiQet al

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Erythropoietin, iron depletion, and relative thrombocytosis: a possible explanation for hemoglobinsurvival paradox in hemodialysis

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