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Another layer of mechanistic insight comes from therapeutic modeling: Fang et al

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138 The interaction between CST1 and GPX4 improves the stability of GPX4 protein and reduces the intracellular ROS, thus inhibiting ferroptosis

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Another essential aspect is ensuring an adequate intake of the amino acids glycine and cysteine, which are the building blocks for glutathione synthesis

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383,384 Direct targeting of pathogenic T cells constitutes a widely investigated therapeutic strategy (Fig

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