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10.1016/s0928-4257(99)00119-9 112 SikiricP.MikusD.SeiwerthS.GrabarevicZ.RucmanR.PetekM.et al (1997b)

Although findings in the literature are sometimes conflicting and overall inconclusive, evidence suggests that a predominantly plant-based dietrich in antioxidants, fiber, and micronutrientsmay be advisable over dietary patterns characterized by excessive consumption of animal products, particularly animal fats and red meat, provided that adequate intake of iodine and other essential micronutrients is ensured

However, other researchers have argued that controversial issues exist because GPNA also inhibits other glutamine transporters, such as SLC38A1, and V-9302 is effective even in SLC1A5 knockout models 206,207

The presumed mechanism of action shows choline being slowly released from lecithin as a precursor for acetylcholine synthesis
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