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Dietary Intervention One World Health Organization report ( Tests show that TMAO levels surge with increasing choline intake and age ( One investigation on dietary interventions ( Numerous inquiries have pointed to the Mediterranean diet (MD) as a strategy for preventing and reducing the risk of cardiovascular and metabolic diseases ( Ligustrum robustum (a new food resource) reduces serum TMA and TMAO levels by moderating gut microbiota, increasing fecal cholesterol excretion, decreasing serum and liver cholesterol levels, and ultimately attenuating diet induced AS ( So far, the need to fundamentally limit the intake of TMAO precursors to alter the production of TMAO remains unclear