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The expression of glial fibrillary acidic proteina marker of activated astrocytesdecreases, enhancing astrocyte glial cell activity (Jiao et al., 2021)
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Ascorbic acid transport and distribution in human B lymphocytes
10.1152/ajpgi.1997.273.1.G7 Am J Physiol Gastrointest Liver Physiol
Intrathecal administration ensures that tofersen targets motor neurons with pinpoint accuracy through cerebrospinal fluid, effectively diminishing cerebrospinal levels of SOD1 protein and plasma levels of neurofilament light chainsbiomarkers that signal the regression of neuronal damage (43)
