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10.1016/j.phymed.2025.156900 262 ZhangJ.GaoP.ChangW

Cel Biol 25 (18), 80448051

In PCOS patients, hyperphosphorylation of serine residues ( e.g ., Ser307, Ser636) on IRS-1/2 suppresses their tyrosine phosphorylation, thereby impairing the downstream PI3K/AKT signaling pathway

The antioxidative properties of SCFAs are thus a key element in the prevention of oxidative stress-related cellular damage, contributing to the maintenance of redox balance both within the gut environment and systemically

In order to mitigate potential drug safety hazards, blood samples were collected for serum biochemical analysis, including typical liver function indicators (ALT and AST) as well as kidney function indicators (BUN and CREA)
