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When B vitamins become depleted, mitochondrial pathways begin to slow down
Moreover, in the adult brain, microglia promote dendritic spine formation through the secretion of brain-derived neurotrophic factor (BDNF)
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Consequently, ROS have far-reaching impacts on the entire lifecycle of an individual, from embryonic development to growth, aging, and disease progression
Together with vitamin E, it modulated the activity of acetylcholinesterase and reduced demyelinating events in different areas of rat brains (Mazzanti et al., 2009)
