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Biochemistry (Moscow), 76(11), 12101219

MD simulations were preceded by two energy-minimization steps: (i) only the solvent and ions were relaxed with position restraints for the solute (500 kcal/mol 2 ) using 1000 steps of steepest descendent minimization followed by 500 steps of conjugate gradient minimization

Single doses of mGluR1 antagonist (JNJ16259685) and fenobam rescued social and repetitive behaviors in eukaryotic initiation factor 4E-binding protein 2 gene ( Eif4ebp2 ) knock-out mice [155], implying that group I mGluRs are a favorable therapeutic target for ASD

As glutathione has become so mainstream, it has become important to understand how glutathione works and what to realistically expect from using it