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Karakasheva TA, Dominguez GA, Hashimoto A, Lin EW, Chiu C, Sasser K, et al

Further work suggests that TB-500 may activate two cell-signaling pathways

Without enough B12, you become deficient, which can lead to severe health problems later in life
Inflammatory modulation

Once the deficiency is addressed, a maintenance dose can be given to keep B12 levels within the optimal range
