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Kung, C., et al., Small molecule activation of PKM2 in cancer cells induces serine auxotrophy

These results verified that ferroptosis was involved in MP-induced BMSC damage and that MT could alleviate this damage by regulating antioxidant proteins

The above mechanism can be seen in Figure 1

The molecular basis for this variability is currently unknown but seems to be independent of the nature of the ABCD1 mutation

Shen et al., 2022), primarily due to their ability to activate the Nrf2 pathway (Yang et al., 2022)
