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By regulating the Nrf2/HO-1 pathway, A5 improves the activity of SOD and GPX and the level of glutathione, reduces the levels of iron deposition, 4-HNE and MDA, thereby improving the ferroptosis of neurons induced by TBI
STAG2 loss-of-function mutation induces PD-L1 expression in U2OS cells
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doi: 10.1210/jc.2015-4251 359
They isolated it, synthesized it, and called it BPC-157
