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There is some evidence that regular use of these medications may slow the progression of the disease

Important: Kojic acid may increase skin sensitivity

Zhang C, Li L, Hou S, Shi Z, Xu W, Wang Q, He Y, Gong Y, Fang Z, Yang Y

In the search for a shortcut to skin lightening, individuals may use OTC creams containing hydroquinone, steroids and other actives may be used

These studies will provide the in vivo proof-of-concept that the strategy of modulating glutamate levels can be developed for NP therapeutics and for opioid dependence, two independent diseases that may develop as co-morbidities in patients who failed first- and second-line NP therapies and resorted to opioid use