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Epithalon also appears to inhibit the activity of Caspase-3, a key enzyme that is considered to promote apoptosis (programmed cell death)

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[PubMed] [Google Scholar] 64.Askari HA, Check JH, Peymer N, Bollendorf A

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Remarkably, analysis of gene expression in non-small cell lung cancer patients of the TCGA data bank revealed that there is a significant lower overall survival rate in the subset of patients bearing tumors with unbalanced levels of NRF2/KEAP1 and, as consequence, increased expression of NRF2 target genes