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Description
When NNMT runs hot, as it tends to in enlarged fat cells, more nicotinamide gets pushed toward a dead-end waste product instead of being salvaged back into NAD+
Campdesuner V, Teklie Y, Alkayali T et al
After initial repletion, a maintenance dose is given, often 1,000 mcg intramuscularly every month or every 2 to 3 months, to prevent recurrence of deficiency
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