may 2017 study glutathione sublingual Evaluation of the antioxidant and anti-inflammatory effect of on COPD patients Glutathione deficiency in the pathogenesis
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10.1016/j.ebiom.2017.04.036 111
Strikingly, increasing cellular L2HG levels by knockdown of L2HG dehydrogenase (the only known enzyme that oxidizes L2HG back to -KG) decreased mitochondrial oxygen consumption and lactate production, which indicates that L2HG could inhibit both mitochondrial respiration and glycolysis to blunt their production of NADH and to mitigate attendant reductive stress (72)
10.1016/j.plgene.2020.100237 Plant Gene 30 JonesD
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After 8 weeks, lean mass for GSH + CIT was still greater than PLC
