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This conclusion is further supported by the observation that mice lacking Epac1 , which encodes one of the two isoforms of EPAC in mammals, are more resistant to DIO and have improved glucose tolerance and heightened central leptin sensitivity, as measured through STAT3 activation, compared with control mice 98

The use of HPLC with electrochemical detection can overcome these problems by direct measurement of GSH and GSSG [39,40] but can be very expensive

doi: 10.1016/j.toxlet.2024.08.006

(2021) studied the conjugation of DEX, characterized by its hydrophobic properties, to the hydrophilic compound salvianolic acid B (SAL) by an ester bond resulted in the formation of a nanomolecule employed for otoprotection

XuDLiLZhangXYaoHYangMGaiZet al