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Methods Primers 1 , 59 (2021)

Aliment Pharmacol Ther (2007) 25(9):10617

Coumarin-based compounds have been found to act through a series of complex pathways to target a wide range of diseases

The substance has a strong affinity for macrophages expressing FPR-1 and effectively suppresses the generation of intracellular ROS and inflammatory molecules, including IL-6, TNF-, IL-1, and COX-2 (Fig

Therefore, despite being only a partial effector of carcinogenesis, CBS belongs to a panel of intervening players, including NF-B, KRAS, p53 and Wnt components, that contribute to metabolic rewiring and increased proliferative and invasive potential