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This review does not only provide valuable insights into the application of metabolomics in hepatotoxicity evaluation but also offers a flexible and adaptable framework that can be employed in other research areas where metabolomics approaches could be useful or necessary

J Gastroenterol Hepatol 18:479497 Findley MK, Koval M (2009) Regulation and roles for claudin-family tight junction proteins

The GPx enzyme allows the assessment of oxidative status, by determining its values, in different situations, both normal and pathological

Low levels of B12 are associated with issues such as anxiety, depression, and cognitive decline

Hormones: Estrogen and progesterone, the hormones that stimulate the development of the uterine lining, also appear to promote the growth of fibroids