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Therefore, the lower ratio of GSH/GSSG may indicate higher oxidative stress in cells [10]

This section summarizes the current research status of reported ferroptosis-related pharmacological agents, analyzing their mechanisms of action and therapeutic effects in AD models, aiming to provide theoretical foundations and structural references for future anti-AD drug design based on ferroptosis mechanisms ( Table 1 )

10.1016/j.ecoenv.2018.12.082 149 SdougaD.BrancaF.KabtniS.Di BellaM

These compounds offer distinct advantages over their peptide-based counterparts, including oral bioavailability, improved patient adherence, and the potential for broader therapeutic applications

Santa Cruz Biotechnology, Dallas, TX, USA), and monoclonal anti-rabbit Gpx4 (1:1000, 67763-1-Ig