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Excess -tocopherol decreases extrahepatic phylloquinone in phylloquinone-fed rats but not menaquinone-4 in menaquinone-4-fed rats

The vast microbial genetic reservoir within the gut enables the gut microbiota to establish a mutualistic relationship with the host, performing critical functions such as fermenting dietary fibers to produce short-chain fatty acids (SCFAs), synthesizing vitamins (e.g., B12 and K), metabolizing xenobiotics, and competitively excluding pathogens [30]

Lifespan and healthspan extension by resveratrol

J Neurophysiol 103(5):28462856
10.1021/bi800498g 121 LuJ.HolmgrenA