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By synthesizing current evidence, this review aims to clarify the potential role of HPA axis dysregulation and hippocampal dysfunction in ME/CFS-related cognitive dysfunction, and to provide insight into potential targeted interventions

In European countries, it has been estimated that the prevalence of Biermers disease is approximately 4% of the population

In addition, epidemiological studies should focus on sexually active adolescents and young adults, collecting detailed behavioral data to distinguish sexual from environmental transmission

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Inter-individual sensitivity to light intensity is modulated by intrinsic factors: older adults often exhibit heightened melatonin suppression (57)