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These variants have also been associated with the development of symptoms of Parkinsons Disease in PEO patients (Reeve et al., 2013)

Ontogeny and cellular localization of the pyruvate recycling system in rat brain

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Among these trials, one study aiming at hepatocellular carcinoma using a humanized monoclonal antibody against Dickkopf-1 (DKK1), DKN-01, is involved in phase I and II trials (ClinicalTrials.gov Identifier: NCT03645980)