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U.et al (2013)

Among all DE genes, 52 previously annotated lncRNAs in hepatocytes were differentially expressed by TCDD, many of which are associated with steatosis, fibrosis, and hepatocellular carcinoma

However, although erastin shows antitumor effects, it has not entered clinical trials because it is poorly soluble in water, and its metabolism in vivo is unpredictable

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