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Role and mechanism of ROS scavengers in alleviating NLRP3-mediated inflammation

Studies have characterised MC1R-mediated anti-inflammatory signalling in macrophage and neutrophil models , examining cAMP-mediated NF-B suppression and cytokine production inhibition and and have examined MT-1s effects in inflammatory bowel disease, arthritis, and ischaemia-reperfusion injury models where melanocortin anti-inflammatory biology has been characterised

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doi: 10.1523/JNEUROSCI.3133-07.2007

One of drosophilas greatest advantages is its extensive genetic toolkit, which can be used to create genetic screens that find the genes required to regulate obesity