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The subthreshold micropulse yellow laser (SMYL) treatment effectively treats macular edema by stimulating retinal pigment epithelial (RPE) cells with light, reducing the number of inflammatory cytokines and hyper-reflective retinal spots (HRS) ( Blue light damage to the eyes has led to an increase in various ophthalmic diseases such as age-related macular degeneration (AMD) (Jin and Jeong, 2022

Type 2 diabetes In type 2 diabetes, metformin therapy is associated with B12 deficiency, resulting in a 10% higher risk of developing B12 depletion
The therapeutic benefits of vitamin B12 supplementation in sleepwake disorder management were also suggested by Maeda et al., who noted its role in regulating circadian rhythms [37]

[DOI] [PMC free article] [PubMed] [Google Scholar] 12.Granneman JG, Moore H-PH, Granneman RL, Greenberg AS, Obin MS, Zhu Z
