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Tesori- ere and M

Its essential to be aware of these and seek medical attention if they occur

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Curcumin downregulates P-glycoprotein (P-gp) expression, increasing the accumulation of doxorubicin in drug-resistant breast cancer cells, thereby restoring their sensitivity to the drug (Yan et al., 2024)

The carbon skeleton of glutamate via entering the Krebs cycle is converted to malate, which is ultimately turned to pyruvate by the malic enzyme (ME)
