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Artificial microbiome heterogeneity spurs six practical action themes and examples to increase study power-driven reproducibility (in Eng)

Subcutaneous administration of vitamin B12 is sometimes employed, especially in patients with congenital cobalamin metabolism disorders who require high doses to maintain normal metabolic pathways

Individuals at higher risk include older adults with reduced stomach acid production, people with gastrointestinal conditions affecting absorption, strict vegans, and those taking medications like metformin or proton pump inhibitors

Hydration Dehydration is an underappreciated risk during this combination

Importantly, all ASVs within six of the genera mapped to identical species when analyzed by both methods