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The PDP1 phosphatase complex is widely distributed and is considered a major regulator of the activity of the PDH complex

Both paclitaxel and docetaxel are extensively metabolized, via cytochrome P 2C8 and 3A4, respectively, albeit pharmacological activity of these metabolites is modest at best and their contribution to the development of CIPN is unknown
[On the mode of incorporation of shikimic acid into 2-hydroxy-1,4-naphthoquinone (lawsone)]

DPOAE measurements On the day of the last dosing in the experiment (15th day), rats were anesthetized by intraperitoneal injection of ketamine (50 mg/kg bwt) and xylazine (5 mg/kg bwt)

Town, T., Jeng, D., Alexopoulou, L., Tan, J