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Together, these insights aim to refine diagnostic precision, personalize treatment, and improve clinical outcomes across the heterogeneous ILD spectrum
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-Galactosidase (-gal) is an enzyme that breaks down glycosidic bonds and hydrolyzes -galactosides into monosaccharides
Overexpression of SIRT6 inhibits the ubiquitin proteasome system and promotes HIF-1 accumulation, upregulating the expression of VEGF, angiopoietins1 (Ang1), Ang2, and platelet-derived growth factor-BB (PDGF-BB), consequently enhancing migration, invasion, and proliferation of human umbilical vein endothelial cells (47, 48)
