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Vigorous shaking can denature the protein structure, reducing potency and creating aggregates that may cause injection site reactions
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Researchers who rush the escalation tend to experience more severe nausea, which can lead to skipped doses, inconsistent protocols, and ultimately worse outcomes

This boost delivered in a controlled setting can help promote balance

Phase 2 trials showed 17.5% weight loss at 24 weeks and 24.2% at 48 weeks at the 12mg dose
