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( Although the current findings were based on a PPA-induced model of ASD, which primarily reflected environmental and metabolic contributions, the observed therapeutic effects of luteolin particularly its antioxidative, anti-inflammatory, and gut-protective properties suggested that it may also be beneficial in genetic models of autism

The remaining missing values were imputed with the R package missForest with default parameters

Nat Commun 12(1):2722, 2021