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Mitochondrial dysfunction appears pervasive in ASD pathophysiology

doi:10.1186/s12989-020-00394-8 Gao Y, Huang W, Yu P, et al

Nature 472:57-63

However, in a similar study performed to evaluate the effects of pyruvate with increased frequency of dosing (500 mg/kg i.p., 6 days a week) in SOD1 G93A mice, pyruvate was not able to alter the onset of the disease or survival of mice (Esposito et al., 2007)

According to the position statement issued by ACAAI and ACOG, chlorpheniramine was selected as one of two recommended antihistamines in pregnancy (the other is not available in the U.S.)
