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Science, 253(5022), 905909

[DOI] [Google Scholar] 88.Raina N., Rani R., Khan A., Nagpal K., Gupta M

Despite its multifaceted therapeutic potential, the clinical performance of silymarin is hampered by poor oral bioavailability due to low aqueous solubility, hydrophobicity, enzymatic degradation, limited intestinal absorption, and rapid systemic clearance

506 However, clinical trials for C9ORF72-targeted therapies WVE-004 and Tadnersen (IONIS-BIIB5Rx) have been terminated due to poor efficacy

Speaking about BPC-157, he said, its insane how well it works. McGuire, the University of Utah chief resident, suspects some of the hype comes down to pop science podcasting and its business model