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In addition, when one separates the water-soluble crystallins by size, an increasing proportion is found in high molecular aggregates

We then gave these filtered media to gsh1 -cells and incubated them at 30.0 O C (green curves)

We used a semiquantitative neuropathological scoring system, and the sum of the analyzed affected areas (04) (i) and karyopyknotic cells in the brain areas (04) (ii) made (i) + (ii) a combined score (08) as follows

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