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Pharmacological inhibition of apical sodium-dependent bile acid transporter changes bile composition and blocks progression of sclerosing cholangitis in multidrug resistance 2 knockout mice

Cell Cycle 17 , 16021613

These results suggest that low glutathione tumor levels may be a sensitivity marker for GCLC inhibitors

In addition, the pathological process of redox imbalance is also accompanied by enhanced catabolism, inflammation, and weakened metabolism, which will continually aggravate the senescence of NPCs [9,10,11]
