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[DOI] [Google Scholar] 116.Sripakdee T., Mahachai R., Chanthai S

doi: 10.1093/jn/128.4.707

Lipoxygenase/Leukotriene Pathway Activation of 5-lipoxygenase (LOX) in ( primarily expressed in leukocytes ) results in the conversion of arachidonic acid to leukotrienes that function as inflammatory mediators (Wikipedia) resulting in: bronchoconstriction increased secretion of mucus leukocyte chemotaxis histamine release This pathway has its greatest clinical relevance in the pathophysiology of asthma

Dosage Used: The amount of product used plays a big role in pricing, like treating a small under-eye area requires less product and costs less

A., Rotrosen J., Edson R., Lavori P., Lohr J., Hitzemann R., et al