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GLP-1 receptor activation suppresses appetite, slows gastric emptying, enhances glucose-dependent insulin secretion, and helps restrain inappropriate glucagon activity

Before the approval of PT-141, there were limited treatment options for HSDD

Disruption of the normal gut microbiota may lead to intestinal dysbiosis, barrier dysfunction, bacterial translocation, and excessive production of uremic toxins, including indoxyl sulfate (IS), p-cresyl sulfate (p-CS), and trimethylamine-N-oxide (TMAO), all of which are implicated in the variant processes of kidney diseases development (Chen et al., 2019)

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Additionally, it helps replenish other antioxidants such as vitamins C and E and supports liver functions necessary for filtering toxins and maintaining overall health