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Both UPR and EOR are caused by protein processing disorders, while the sterol regulatory cascade is triggered by the loss of cholesterol synthesized on the ER surface

Curr Res Food Sci 6:100448
10.2174/0113894501306302240526160804 8 AndrewsJ

Metabolic dysregulation with atypical antipsychotics occurs in the absence of underlying disease: a placebo-controlled study of olanzapine and risperidone in dogs
In dogs with chronic liver diseases, bile acid-induced activation of Kupffer cells and hepatic stellate cells can promote fibrogenesis and worsen liver damage
