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One characteristic of renal cell death and a potential contributor to gentamicin-induced ARF is caspase-3, an essential component of programmed cell death (apoptosis) 88

The use of nalbuphine, a blocker of - and -opioid receptors, also disrupted the effect of GLP-1RAs on reducing TNF- levels, highlighting the essential role of these opioid receptors in the anti-inflammatory effects mediated by GLP-1RAs

10.1016/j.cell.2017.07.050 51 GvozdjakovaA.KucharskaJ.DubravickyJ.MojtoV.SinghR

doi: 10.1021/mp200394t
