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Description
Ayoub N, Jeyasekharan AD, Bernal JA, Venkitaraman AR

These medications appear to interfere with folate metabolism, which is closely linked to B12 function, and may also directly affect the vitamins absorption

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In some embodiments, the otoprotectant is a compound of Formula (IX) having the structure of Formula (IXa): In some embodiments, the otoprotectant is a compound of Formula (X): wherein: X is a single bond, double bond, CH 2 , or O

The usual dose for vitamin B12 injections is 1000 mcg (1 mg), given by injection
