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The activation of microglia is regulated by pattern recognition receptors (PRRs), including Toll-like receptors (TLRs) and nucleotide-binding and oligomerization domain (NOD)-like receptors (NLRs), which can recognize pathogen-associated molecular patterns (PAMPs) and damage-associated molecular patterns (DAMPs) (Lopez Rodriguez et al., 2021
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Calder PC, Carr AC, Gombart AF, Eggersdorfer M (2020) Optimal nutritional status for a well-functioning immune system is an important factor to protect against viral infections
One striking example that demonstrates the interconnectivity between mitochondrial respiratory chain dysfunction, mitochondrial oxidative stress, and cardiac dysfunction is the mitochondrial polymerase mutant mice (the mutator model)

J Pharmaceut Anal
