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Description
As the biosynthesis process depends on the addition of nitrogen sources, such as glycine and hypoxanthine, selection for strains resistant to the adenine antimetabolite, 4-aminopyrazolo (3, 4-d) pyrimidine, improved production (Park et al., 2007, 2011
Cell 124 , 12991299
Brain and plasma levels of tryptophan also increased significantly following oral repeated administration of NSO
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