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The aim of this project is to understand the role of Lecs and LecRKs

Treatment of large CT26 colon cancer tumors (1000 mm 3 ), with a volume known to be refractory to immune checkpoint therapy (ICT), with vitamin C in combination with the ICTs anti-CTLA-4 and anti-PD-1 led to tumor regression

the various methods differ in sensitivity, specificity (in particular, in distinguishing GSH from GSSG and other thiols), and susceptibility to matrix interference [119]

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28 Additionally, a 16-week trial of supplementation with GlyNAC (which boosts glutathione levels) in older adults improvedand in some cases reversedmultiple hallmarks of aging, including inflammation, mitochondrial dysfunction, and oxidative stress