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7 Methods In this study, we conducted a comprehensive literature search across several prominent databases, including PubMed, Embase (via OVID), Cochrane CENTRAL, CINAHL, and Web of Science, with data retrieval extending through December 2024

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A number of chemicals, including unleaded gasoline, 2,2,4-trimethylpentane, 1,4-dichlorobenzene and d -limonene, a natural product found in citrus oils, have been found to cause kidney tumours specific to male rats by binding to a specific protein in the proximal tubules of male rats, alpha 2u -globulin, leading to hyaline droplet accumulation (Dietrich & Swenberg, 1991