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This can lead to palpitations, irregular heart rhythms, or even chest pain

Although biotin competes with vitamin B5 for the same absorption mechanism, this is irrelevant if biotin is taken in moderate amounts

Metformin, commonly prescribed for type 2 diabetes, is known to reduce B12 absorption over time, as highlighted in MHRA safety updates

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Homocysteine and cardiovascular disease Observational studies indicate that even moderately elevated blood concentrations of homocysteine raise the risk of cardiovascular disease (CVD), although randomized controlled trials of homocysteine-lowering therapy have generally not translated to reductions in adverse cardiovascular outcomes (26, 27)